What is follicular tumor
Follicular tumors are tumors that originate from lymphoid follicles, often found in lymph nodes or lymphoid tissue. In recent years, with the deepening of medical research, the diagnosis and treatment options for follicular tumors have been continuously improved. This article will introduce you to the relevant knowledge of follicular tumors in detail from the aspects of definition, classification, symptoms, diagnosis and treatment.
1. Definition of follicular tumors
Follicular tumors are tumors of the lymphatic system that originate primarily from B lymphocytes. It usually presents with enlarged lymph nodes and may progress to follicular lymphoma (FL), a common form of non-Hodgkin lymphoma (NHL). The pathogenesis of follicular tumors is closely related to genetic variation, immune system abnormalities and other factors.
2. Classification of follicular tumors
| Classification | Description |
|---|---|
| Follicular lymphoma (FL) | The most common follicular tumor is an indolent lymphoma that grows slowly. |
| follicular thyroid cancer | It originates from thyroid follicular cells and is an endocrine system tumor. |
| Other follicular tumors | Including rare types such as follicular helper T-cell lymphoma. |
3. Symptoms of follicular tumors
Symptoms of follicular tumors vary depending on the type and location. Common symptoms include:
| Symptoms | Description |
|---|---|
| swollen lymph nodes | It is a painless swelling that usually occurs in the neck, armpits, or groin. |
| fatigue | Because tumors consume energy, patients tend to feel tired. |
| Fever and night sweats | Some patients may experience unexplained fever or night sweats. |
| weight loss | As the tumor progresses, patients may lose significant weight. |
4. Diagnosis of follicular tumors
The diagnosis of follicular tumors requires a combination of clinical manifestations, imaging examinations, and pathological analysis. The following are common diagnostic methods:
| diagnostic methods | Description |
|---|---|
| lymph node biopsy | Pathological examination is performed by removing part of the lymph node tissue. |
| blood test | Tests the blood for tumor markers or abnormal cells. |
| Imaging examination | Including CT, MRI or PET-CT to assess tumor extent and staging. |
| bone marrow aspiration | Check the bone marrow for tumor invasion. |
5. Treatment of follicular tumors
Treatment options for follicular tumors vary by type and stage and include the following:
| Treatment | Description |
|---|---|
| Watch and wait | It is suitable for indolent lymphoma and may not be treated temporarily when there are no obvious symptoms. |
| Chemotherapy | Drugs are used to kill tumor cells, often for advanced tumors. |
| radiotherapy | Local treatment is suitable for early or localized lesions. |
| Immunotherapy | Rituximab, for example, targets B cell surface antigens. |
| targeted therapy | Drugs that target specific genetic mutations, such as BTK inhibitors. |
6. Prognosis of follicular tumors
The prognosis for follicular tumors varies depending on the type and stage. Follicular lymphoma has a higher 5-year survival rate, but it can relapse. Early diagnosis and standardized treatment are the keys to improving prognosis.
7. The relationship between hot topics in the past 10 days and follicular tumors
Recently, advances in research and treatment of follicular tumors have become a hot topic in the medical community. The following is the popular content in the past 10 days:
| hot topics | Content summary |
|---|---|
| New targeted drugs | Research shows that new BTK inhibitors have significant effects on follicular lymphoma. |
| Immunotherapy breakthrough | CAR-T cell therapy makes progress in relapsed/refractory follicular lymphoma. |
| early screening technology | Liquid biopsy technology provides new ideas for the early diagnosis of follicular tumors. |
Follicular tumor is a complex disease, but with the advancement of medical technology, the quality of life and prognosis of patients are constantly improving. If you or someone around you develops related symptoms, it is recommended to seek medical treatment promptly for early diagnosis and treatment.
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